http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1689717-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-472 |
filingDate | 2004-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2007-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f89eb891cb284998c622d503d61494c6 |
publicationDate | 2007-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1689717-B1 |
titleOfInvention | Substituted isoquinolines useful in the treatment of diseases such as cancer and atherosclerosis |
abstract | A compound of Formula (I): or a salt or solvate thereof, wherein: One of R1 and R2 is H and the other represents -NHCONHR4, wherein R4 represents a phenyl or naphthyl group which may be optionally substituted by one or more substituents independently selected from -C1-6 alkyl, -C1-6 haloalkyl, halogen, C1-6 alkoxy, C1-6 haloalkoxy, OH, NO2, C3-7 cycloalkyl, indanyl, or R4 together with the NH to which it is bonded forms a morpholino group; and R3 is H or NHR5 wherein R5 is H, -quinolinyl or -isoquinolinyl, -(CONH)p phenyl wherein p is 0 or 1 and the phenyl is optionally substituted by one or more substituents independently selected from halogen, -C1-6 alkyl, -C1-6 haloalkyl, -morpholino, -SO2NH2, and methyl substituted benzothiazole. |
priorityDate | 2003-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 936.