| abstract |
The invention relates to the use of a virus, preferably an adenovirus for producing a medicament, said virus being replication deficient in cells that do not contain YB-1 in the nucleus. The virus codes for an oncogen or oncogen product, in particular an oncogen protein, which transactivates at least one viral gene, preferably an adenoviral gene, said gene being selected from the group containing E1B55kDa, E4orf6, E4orf3 and E3ADP. |