Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66c1b22707b0276e3078713a6ddcba91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24221 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-707 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
filingDate |
2004-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8539040c79fb43b3585a41e927b26de7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54afd168c728c8902e96deec6b5d5c19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34771a8594d7695b26ec7efdf7f7a011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58d1afb67bc854a9bd69af2a98cbb88d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_864f11a16e4abe4dd2235a5308d6d3dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b37845fc191272ccb319cf178000f82 |
publicationDate |
2006-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1685238-A2 |
titleOfInvention |
Hcv replicons containing ns5b from genotype 2b |
abstract |
The present invention features methods for enhancing the ability of a genotype 2b NS5B sequence to function in a replicon, for producing replicons containing a functional genotype 2b NS5B, and for using replicons to measure the ability of a compound to affect HCV replication that is sustained with the genotype 2b polymerase. Also featured is a genotype 1b NS4B adaptive mutation. The ability to produce replicons containing a functional genotype 2b NS5B is illustrated by the production of chimeric replicons based on HCV genotype 1b where substantially all the NS5B sequence is replaced with a genotype 2b NS5B. |
priorityDate |
2003-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |