Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28a89f8dab024e02ae765d1273e716f1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 |
filingDate |
2004-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c49a14064e7f6c036599d6ab67e78457 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f8730d5fb2b70896c490f26982a375f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c65f0be60cdc3432f14071f2c00a89d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92281e0488883909c7994007e89d9bec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb8c6f2207f76113c1b55dd772d2949d |
publicationDate |
2011-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1680681-B1 |
titleOfInvention |
Method and apparatus for assessing polypeptide aggregation |
abstract |
A method of determining aggregation rate data predicting an aggregation rate of a polypeptide defined by an amino acid sequence, the method comprising determining a hydrophobicity value, a charge value, and at least one shape propensity value for said sequence; identifying one or more aggregation-influencing patterns within said sequence; deterrnining a pattern value for the sequence responsive to said identifying; and dutermining said aggregation rate data by determining a weiglited combination of said hydrophobicity value, said charge value, said at least one shape propensity value, said pattern value and at least one factor extrinsic to said amino acid sequence. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10993997-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11452768-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10975442-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11725237-B2 |
priorityDate |
2003-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |