| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c79ca5908b46e5878e9bc559c608d80 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-008 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 |
| filingDate |
2004-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b61ebd4b188415e764fb7bc6b17dd7c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb9a79fe5cbf1161cf9197129481e759
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6fb92bbfa2fee0b5b18e6c270a4da91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6266ec9c53aa99876f19bcd1b19bbd4e |
| publicationDate |
2007-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1678198-A4 |
| titleOfInvention |
SIDE CHAIN DEUTERATED AMINO ACIDS AND METHOD OF USE |
| abstract |
Protein structural determination using NMR techniques is improved through use of proteins in which one or more amino acids in the peptidic sequence are isotopically enriched in the sidechain with 2H and are isotopically enriched on the backbone with 13C, 15N, 2H or any combination thereof. This invention provides amino acids isotopically enriched as above, which can be used to synthesize isotopically labeled proteins and peptides for protein structural determinations by NMR, and methods for their synthesis. Other embodiments of the invention include peptidic molecules, media for peptidic molecule expression, methods of making isotopically labeled peptidic molecules and methods of determining structural information of a peptidic molecule. |
| priorityDate |
2003-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |