Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd2955c27933428d2aa5701f1ba09d5c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 |
filingDate |
2004-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7931e15cffb52f732cb05d8cc2b81b0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a46b1d19eea5758bee113c352089f51d |
publicationDate |
2006-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1678192-A1 |
titleOfInvention |
Process for the preparation of doxifluridine |
abstract |
A process is described for the preparation of doxifluridine of formula (I) at high yields and with reduced formation of impurities, which comprises the reaction of coupling of a compound of formula (III) with a compound of formula (IV), as defined in the description, in the presence of a Lewis acid and in an inert organic solvent, characterized in that said Lewis acid is added at a temperature below 0°C. |
priorityDate |
2003-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |