http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1674458-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f7b665fb8f15d0e2b0911539d39f8a2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-12 |
| filingDate | 2004-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9667872df239091d92dedcf26ab2c637 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a780feb6b20f7c1e1a43b4b67eb6d0fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba599d3b6b284ff08376c5103ef9c3d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e79c4f002342866935bed46e266d9494 |
| publicationDate | 2006-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1674458-A1 |
| titleOfInvention | Process for obtaining enantiomers of cizolirtine |
| abstract | A process is described for the preparation of a precursor alcohol of Cizolirtine, (±)-2-[phenyl(1-methyl-1 H -pyrazol-5-yl)methoxy]- N,N- dimethylethanamine and its enantiomers, it comprises the asymmetric reduction of a prochiral ketone in the presence of a chiral ruthenium (II) catalyst system comprising at least a bidentate phosphorous-containing ligand and a diamine ligand to render chiral alcohols. The chiral alcohols are further O-alkylated to render the corresponding pharmaceutically active ethanamines. |
| priorityDate | 2004-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.