http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1667987-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bba842fc4d37dfcaced1b55bc0c91c7c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-88 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-88 |
filingDate | 2004-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2008-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b8627dd8fcd2a2aa39ef3cc753049d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da16aea85883c31b6d15e0eaccb4734f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_becdeb1b43f34f1e2fc6c4279e9b8c8a |
publicationDate | 2008-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1667987-B1 |
titleOfInvention | Process for the production of mycophenolate mofetil |
abstract | The present invention relates to a new and economically attractive process for the production of mycophenolate mofetil in a high degree of pharmaceutically acceptable purity, which comprises the reaction of a reactive derivative of mycophenolic acid with 4-(2-hydroxyethyl)morpholine under acidic reaction conditions and the subsequent extraction of the pure mycophenolate mofetil through salt formation and release of the free base. A further aspect of the invention relates to the purification of mycophenolate mofetil by removing its by products, in particular its dimeric by-products, by means of treatment with a primary or secondary amine. |
priorityDate | 2003-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 135.