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filingDate 2004-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2011-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2663cd5a454d5c54789f82a070203af1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d7f29fa527f8009a99b9a73bac9e8ff
publicationDate 2011-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1664722-B1
titleOfInvention Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
abstract A polyelectrolyte having multiple exposed functional groups, each such group being capable of covalently bonding to a molecule, is immobilized on a surface for the purpose of bonding to a biomolecule. The biomolecule can be, for example, a nucleic acid, e.g., an amine functionalized oligonucleotide. The polyelectrolyte can include, e.g., BSA (Bovine Serum Albumin) which is bound to a functionalized surface using a covalent immobilization strategy, e.g., reaction with the surface of a tosyl-activated microparticle. Following such reaction, exposed reactive functional groups on the protein, such as amine, carboxyl, thiol, hydroxyl groups can further be utilized to covalently couple the oligonucleotide of interest using suitable chemistry.
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type http://data.epo.org/linked-data/def/patent/Publication

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