http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1660532-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_784d21188bb2cdcad1f9e123bd57aa18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9017caa87c287b8361ef8de64f411d9f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745 |
| filingDate | 2004-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38cf1d9462bc85dd88ebe8c388ac5a36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d75feaaf495ed5d57a012525b50c7026 |
| publicationDate | 2006-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1660532-A1 |
| titleOfInvention | Fusion polypeptides, and use thereof in antivascular tumor therapy |
| abstract | Disclosed is a fusion polypeptide comprising a) a peptide of 3 to 30 amino acids, which allows selective binding of the fusion polypeptide to tumor vessel endothelial cells, and b) the tissue factor TF or a fragment thereof, the tissue factor and the fragment being characterized by being able to activate coagulation when the fusion polypeptide binds to tumor vessel endothelial cells. Peptides a) and b) are coupled to each other directly or via a linker comprising up to 15 amino acids while the peptide which allows selective binding of the fusion polypeptide to tumor vessel endothelial cells is coupled to the C terminal of the peptide that is able to activate coagulation when the fusion polypeptide binds to tumor vessel endothelial cells. |
| priorityDate | 2003-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 159.