| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55bc2bae9f65cfaede67b62128f00e9b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-916
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-912
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-325 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6843
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
| filingDate |
2004-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1687cd58bd254b360fc97eda25e7250d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bad8913a69db12bfc45655ff4b37964
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2a020e14591ec8d7c20039c2e7549d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de6a1f291f8025f950b75bbdbe92c661
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f09e6eb6f9f79594e941a9ff30c26fe8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6457a5706014d1eda57717ee24c84697
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_138c221b5f967b4a63714d43198aadc4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd2b8a6f926aad55841735fd1fb39545 |
| publicationDate |
2006-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1656560-A2 |
| titleOfInvention |
Diagnostic markers and pharmacological targets in heart failure and related reagents and methods of use thereof |
| abstract |
The invention identifies genes whose expression is upregulated or downregulated following mechanical offloading in subjects with heart failure. The invention provides compositions comprising a targeting agent conjugated to a functional moiety, wherein the targeting agent selectively binds to a polypeptide encoded by one of these genes. The functional moiety can be an imaging agent, therapeutic agent, etc. The invention further provides methods for providing diagnostic or prognostic information related to heart failure involving detecting expression or activity of an expression product of one or more of the identified genes. The invention further provides diagnostic and therapeutic methods comprising detecting or administering an apelin peptide to a subject. |
| priorityDate |
2003-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |