| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fc6c2e9e63b6561f2f46b1de31f6379 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1096
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-006 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 |
| filingDate |
2004-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ea7af3284e79417f39ba1343199ba72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8daf6dcddc970bccd0f473618fa8c2e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77f991c67fcdd601ccbc929479ec56b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87e13cd9027cc8fd705d97ff3908805b |
| publicationDate |
2006-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1646718-A2 |
| titleOfInvention |
Methods for the stereoselective synthesis and enantiomeric enrichment of b-amino acids |
| abstract |
The present invention relates to methods for the stereospecific synthesis and for the enantiomeric enrichment of Beta-amino acids. A novel D-Beta-aminotransferase, which exhibits stereoselectivity for D-Beta phenyalanine D-3-amino-3-phenylpropanoic acid, was purified from a newly-isolated strain of Variovorax paradoxus. A novel L-Beta- aminotransferase was purified from a newly-isolated strain of Alcaligenes eutrophus. The D- and L-Beta-aminotransferases can be used to facilitate the stereoselective biosynthesis of Beta-D-phenylalanine or Beta-L-phenylalanine, from a mixture of L-glutamic acid or L-alanine, respectively, and 3-keto-3-phenypropanoic acid in the presence of the cofactor pyridoxal photephate. |
| priorityDate |
2003-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |