abstract |
Provided are compounds of a formula (I) and their pharmaceutically-acceptable salts:n nwherein X1, X2 and X3 each independently represent N or CH; W represents the following formula (II):n nor the following formula (III):n nY represents a group of a formula (IV):n nThe compounds have a histamine-H3 receptor antagonistic or inverse-agonistic activity and are useful for remedy and/or prevention of obesity, diabetes, hormone secretion disorders, sleep disorders, etc. |