| abstract |
The present invention provides a compound of the formula (I) wherein R is -H, or -C1-C4 alkyl; R1 is -H, -OH, -O(C1-C4 alkyl), -SO2(C1-C4 alkyl), or halo; X is -O-, -CH2-, or -C(O)-; X1 is -O- or -NR2-; R2 is -H or -CH3; Y is -S-, -CH2CH2-, or -HC=CH-; m is 0, 1, 2, or 3; and n is 0 or 1; or a pharmaceutically acceptable salt thereof; pharmaceutical compositions thereof; and methods for inhibiting a disease associated with an aberrant physiological response to endogenous estrogen. |