Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_604a4da0d04fcf667e2b9ceab58130f2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0657 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-54 |
filingDate |
2004-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2010-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c33c7653eda38b08a9ccaf80e044298 |
publicationDate |
2010-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1639003-B1 |
titleOfInvention |
Use of cardiotrophin to modulate stem cell proliferation |
abstract |
Methods of promoting stem cell proliferation comprising contacting the cells with cardiotrophin-1 (CT-1) are provided. The methods may further comprise contacting the stem cells with one or more stem cell modulators that promote differentiation of the stem cells. Methods of inhibiting stem cell proliferation comprising contacting the cells with one or more CT-1 inhibitor are also provided. The methods can be used to promote or inhibit stem cell proliferation in vitro and in vivo. Therapeutic applications of the methods in the replacement of damaged or defective tissue or in the inhibition of inappropriate cell proliferation are also provided. |
priorityDate |
2003-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |