http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1637515-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10e4b1416c6e66e0ade5429212414964 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-84 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-42 |
filingDate | 1999-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4bb8a4a0e540a32d28f8f8c002b3c48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e432ef09eadbe79803eb00de15660d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eff86049181af6760150bd296ef7781b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0735408ed4e54eb5833e944c7ab31af4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b55e4f4584c9bce5941fe0d477e82ab |
publicationDate | 2006-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1637515-A1 |
titleOfInvention | Sertraline hydrochloride polymorphs |
abstract | The present invention is directed to forms II, III, V, VI, VII, VIII, IX and X of sertraline hydrochloride and novel methods for their preparation. According to the present invention, sertraline hydrochloride polymorph II may be produced by slurrying sertraline hydrochloride polymorph VI in aprotic organic solvent. Sertraline hydrochloride polymorphic form III may be produced by heating sertraline hydrochloride polymorphs V and VI. Sertraline hydrochloride forms V and VI may be produced from either sertraline hydrochloride or sertraline base by crystallization. Sertraline hydrochloride Form VII may be produced by suspending sertraline chloride polymorph V in water, followed by filtration. Sertraline hydrochloride Forms VIII and IX may be produced by suspending sertraline base in water followed by acidification and filtration. Sertraline hydrochloride Form X and be produced by suspending sertraline hydrochloride in benzyl alcohol with heating, followed by filtration. |
priorityDate | 1998-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.