| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a445bf3b022926f4cfccd3d23d1ee302 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
| filingDate |
2004-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1572595dcbdeb0161e15a8ca85b37f8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08b9630694e5a569a3b29f11a0695223
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3479ae171a36c353564331bfde1e2d04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b487665e0acde873ea0ed8d3c1d7460
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e0ac01d681b976a7f871466db420996 |
| publicationDate |
2006-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1633770-A2 |
| titleOfInvention |
Double-stranded ribonucleic acid with increased effectiveness in an organism |
| abstract |
The present invention relates to a method for the targeted selection of a double-stranded ribonucleic acid (dsRNA) consisting of two single strands that exhibits increased effectiveness in inhibiting the expression of a target gene by means of RNA interference, wherein at least end of the dsRNA comprises a nucleotide overhang of 1 to 4 unpaired nucleotides in length; wherein the unpaired nucleotide adjacent to the terminal nucleotide pair comprises a purine base; and wherein the terminal nucleotide pair on both ends of the dsRNA is a G-C pair, or at least two of the last four consecutive terminal nucleotide pairs are G-C pairs. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9957505-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9200276-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110042099-A |
| priorityDate |
2003-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |