Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cacd466317f39044a5d62488392e3d6b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G61-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-2208 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0489 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G79-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 |
filingDate |
2004-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8314099f5c9c8b32e6496f7fc699d849 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d028d2239fadf3c5c04febd8d5e17938 |
publicationDate |
2012-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1624901-B1 |
titleOfInvention |
Prosthetic groups attached to stannylated polymers for the synthesis of radiopharmaceuticals |
abstract |
The present invention relates to compositions and methods for preparing radiopharmaceutical compounds in high chemical-purity and isotopic-purity. The present invention provides polymer-bound precursors to radiopharmaceutical compounds that can be converted to radiopharmaceutical compounds in one step. In a preferred embodiment, a radiopharmaceutical precursor is bound to a polymeric support via a prosthetic group comprising an alkenyl-tin bond. The radiopharmaceutical precursor is converted to a radiopharmaceutical compound in one step involving cleavage of the alkenyl-tin bond and incorporation of a radioisotope to form the radiopharmaceutical compound. Importantly, the polymeric support containing the toxic tin by-product can be easily removed from the radiopharmaceutical compound by filtration. The present invention can be used to install a large number of different radioisotopes. In a preferred embodiment, the radioisotope is 211At, 123I, or 131I. |
priorityDate |
2003-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |