| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ddb9f3656270bc5410be3679322fead |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-21 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343 |
| filingDate |
1999-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e5ca600c4959b9f2df2dedf0dc321f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a1f874d1b6101bde41ae96c6233dcd1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24dc3bd606917e275c737b55f197d00f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_096964e35b77ec54e59ab38211499de7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d25ba8f5a3cc28f95825823a755fad05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b491f9a70bd0a701cde5550b5ab82ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_131fdbc23984fbcdd0a56af76617f24c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce17cb5cf42b5921f4e485a73091794f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f187e44aa689acb025d9665c0bf9a7d |
| publicationDate |
2006-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1619191-A2 |
| titleOfInvention |
Process for producing optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl] acetic acid derivatives |
| abstract |
This invention provides a process for producing optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]acetic acid derivatives, which are of value as intermediates of drugs, from inexpensive starting materials without using any special equipment such as that required for super-low temperature reactions. n A process for producing optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]acetic acid derivatives which comprises nreacting an acetic acid derivative at a temperature of not less than -30°C with an enolate prepared by permitting either a base or a metal having a valency of 0 to act on the derivative to produce a hydroxyoxohexanoic acid derivative, nreducing this compound with the aid of a strain of microorganism to provide a halomethyldioxanylacetic acid derivative, ntreating this compound with an acetalizing agent in the presence of an acid catalyst to provide a halomethyldioxanylacetic acid derivative, nreacted with an acyloxylating agent to provide a acyloxymethyldioxanylacetic acid derivative, and nsubjecting this compound to solvolysis in the presence of a base. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012017242-A1 |
| priorityDate |
1998-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |