http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1618387-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c01f70afd053f8f4b4221ce2ef40a41c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2004-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c50530cc628e0931b217aa477d80fd9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af247ae72c941515fe938b033f03c618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f22b5e7edf4a0920847d050e1d39dc0 |
publicationDate | 2006-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1618387-A1 |
titleOfInvention | Screening method for identifying hsp90 modulators |
abstract | A screening method for identifying and/or analysing Hsp90 inhibitors and/or Hsp90 agonists comprises the steps of contacting a compound with at least two of yeast strains A - E wherein each yeast strain comprises expression vectors from which a pair of binding partners for a yeast two-hybrid assay are expressed. The binding partner pairs comprise: A: Hsp90-targeting protein; B: Hsp90-Hsp9O; C: Hsp90-p23; D: Hsp90-E3 ligase; E: Hsp90-Client. Inhibition and/or promotion of dimerisation between the binding partners is then measured. |
priorityDate | 2003-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 446.