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filingDate 2005-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2006-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1614696-A1
titleOfInvention N-methyl-amide derivatives of Carboxymethylcellulose, alginic acid N-methyl-amide or carboxymethyl starch
abstract Carboxymethylcellulose, alginic acid or carboxymethyl starch N-methyl-amides obtainable from methyl-amine, or salts thereof, and from the tetrabutylammonium (TBA) salt of the desired carboxylated polysaccharide, which is in turn prepared starting from the sodium salt or the acid form of the polymer. The N-methyl-amides of the invention are useful in the biomedical field thanks to their valuable chemical-physical and rheological properties, in particular as drug delivery systems of pharmacologically active principles, as mucus and dermal adhesive moisturizing formulations, as medical devices for the therapy of degenerative osteo-arthritis, as medical devices for healing chronic ulcers or bums; for the preparation of highly biotolerated urethral catheters, as highly moisturizing dermocosmetic formulations and cell scaffolds.
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