| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0f4f8190960626ec922a1f03bcd4aba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-28 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 |
| filingDate |
2004-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc127e7f9d4f65d6084020f693b3e045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa437ffc2b0b863fa600cc9022444089
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a6eb8cf096b08b3fa738c2abd082ec3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2592b0e14de6340b89ae92bea995f379
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_057f28e347607fe0375849b76cb2adc2 |
| publicationDate |
2006-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1613760-A2 |
| titleOfInvention |
Fermentation process for the preparation of pravastatin |
| abstract |
The invention relates to a fermentation process for the preparation of substantially pure pravastatin. The process provides a method of producing pravastatin by microbial hydroxylation of compactin (ML-236B) by maintaining a concentration of compactin at not less than 300 µg /ml during the process. The process produces substantially pure pravastatin with reduced related impurities. The invention also relates to pharmaceutical compositions that include the substantially pure pravastatin. |
| priorityDate |
2003-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |