| abstract |
The current situation is such that it is difficult forndrugs to reach posterior tissues of eyeball, such as choroidnand retina, with the result that treating diseases in suchnregions is difficult. Thus, how to attain effective deliverynof drugs is of importance. It has been found that effectivendelivery of drugs to positerior tissues of eyeball, such asnchoroid and retina, especially those wherein vascularizationnhas occurred can be accomplished by systemic administration,nespecially intravenous administration of polymer micellsnhaving a drug incorporated therein. Further, it has been foundnthat when a photosensitive substance is used as a drug and PDTnis carried out, choroidal neo-vessels can be effectively chokednso as to be useful for the treatment of age-related macularndegeneration. |