| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2a9d061bb94edb53550e546189b8d4a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J7-0445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-8206
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J7-0418
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0066
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2202-064
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J7-0427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2202-062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2016-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2016-0036 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M16-142
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M11-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0065 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M16-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J7-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12 |
| filingDate |
1998-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a421c46634313c1d20a7386de8b4997
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9f9b21ebd7f5405b6c1e4653202af3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad3a0337a8fb04a341e4f3902a442436 |
| publicationDate |
2005-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1607086-A1 |
| titleOfInvention |
Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin |
| abstract |
The need for the delivery of insulin by injection can be reduced or eliminatednby delivering an aerosolized monomeric insulin formulation. Repeatability of dosingnand more particularly the repeatability of the blood concentration versus time profilenis improved relative to regular insulin. The blood concentration versus time profile isnsubstantially unaffected by specific aspects of the patient's breathing manoeuver atndelivery. Further, the rate at which blood glucose is lowered is increased by the usenof monomeric insulin. Particles of insulin and in particular monomeric insulinndelivered to the surface of lung tissue will be absorbed into the circulatory system.nThe monomeric insulin may be a dry powder but is preferably in a liquid formulationndelivered to the patient from a hand-held, self contained device which automaticallynreleases an aerosolised burst of formulation. The device includes a sensor which isnpreferably electronic which measures respiratory flow and volume whichnmeasurement can be used to control the point of drug release. |
| priorityDate |
1993-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |