| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b3db7dd56b56cc6d94d0e0cccc38322 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-235
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-54 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0629 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 |
| filingDate |
2005-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c84385525e175bcf4e5c6658d827ad93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e80fea9fcf8f92c612bc164c98ad4a35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02a904d4a0677a37ac5ac5448d5c2aec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94dcb508a43519f0d8a73d7cd549e13d |
| publicationDate |
2005-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1600501-A1 |
| titleOfInvention |
Use of lif for tissue and cellular engineering |
| abstract |
The invention relates to the use of an effective amount of a compound selected from the Leukemia Inhibitory Factor or Leukemia Inhibitory Factor (LIF), a LIF analogue, a LIF mimetic, a product capable of stimulating the expression of Endogenous LIFs and mixtures thereof for (i) promoting the in vitro multiplication of a population of cutaneous stem cells and / or human epidermal progenitors by maintaining them in an undifferentiated state and / or (ii) maintaining and / or increasing their capacity to generate a pluristratified epithelium, in particular a pluristratified epidermis and / or all or part of the cutaneous appendages.n n n It also relates to a method of obtaining a bank or a culture ofncutaneous stem cells and / or human epidermal progenitors undifferentiated innpresence of LIF, a process for obtaining reconstructed epidermis and / or skinsnreconstructed kits for the production of cell banks or reconstructed epidermis,nand uses of LIF especially for the preparation of stem cells ornreconstructed epidermis for the treatment of subjects with damaged skinn(burn victims and subjects with genetic disorders affecting the skin). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10092504-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008020329-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008020329-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9176144-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9066883-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11033587-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2908784-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9486401-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8075920-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8877253-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8460713-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008068422-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008068422-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9314488-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2007285483-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11007385-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8920848-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9999639-B2 |
| priorityDate |
2004-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |