| abstract |
Disclosed is a device for occlusion of blood vesselncomprising a metallic coil, a sustained-release element andna cell growth factor. Examples of the cell growth factorninclude basic fibroblast growth factor (bFGF), acidicnfibroblast growth factor (aFGF), platelet-derived growthnfactor (PDGF), transforming growth factor β1 (TGC-β1),nvascular endothelia growth factor (VEGF) and connective tissuengrowth factor (CTGF). Examples of the sustained-releasenelement include a hydrophilic hydrogel. By using the devicenfor occlusion of blood vessel according to the presentninvention, a blood vessel site such as aneurysm is occluded,nand preferably, organization may be induced in vivo. |