| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8903a516e8bc59fe6f2f31812f04032 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1058 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-01 |
| filingDate |
2004-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6843cbd07eb33807cd31757409753284
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ededef0416dcfebc922600a0bfc7f7e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc1c00d6a835c53d3c152e096beb0e86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa05bbb655e2760ed7331ec5e7e8257d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf8fc1c962a1ed81a6210ddf57f5bd16 |
| publicationDate |
2005-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1597364-A2 |
| titleOfInvention |
Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways |
| abstract |
The invention relates to a novel method for the preparation of evolved microorganisms which permit a modification of metabolic pathways, characterised in comprising the following steps: a) production of a modified microorganism by genetic modification of initial microorganism cells such as to inhibit the production of or the consumption of a metabolite when the microorganism is cultivated in a defined medium which also affects the capacity of the microorganism for growth, b) culture of the modified microorganisms previously obtained in said defined medium to induce evolution in said cells where it might be necessary to add a co-substrate to the defined medium in order to permit said evolution, c) selection of the cells of modified microorganisms which are capable of developing in the defined medium, optionally with a co-substrate. The invention also relates to the strains of evolved microorganisms obtained thus, the genes evolved which code for evolved proteins which may be obtained by means of said method and the use of said evolved microorganisms, genes or proteins in a biotransformation method. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014049382-A2 |
| priorityDate |
2003-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |