| abstract |
The present invention is related to the use of a compound of thengeneral formulan nwherein R is methyl, ethyl, ethyl substituted with one or more fluorine atoms,nor cycloalkyl-(C 3 -C 7 )-methyl optionally substitutednwith one or more fluorine atoms or benzyl optionally substituted with angroup selected from phenyl, furanyl and thienyl which groups arenoptionally substituted with 1-3 substituents from the group hydroxy,nhalogen, C 1-4 -alkoxy, C 1-4 -alkyl, cyano, aminocarbonyl, mono- orndi-C 1-4 -alkylaminocarbonyl; and pharmaceutically acceptablensalts and prodrugs thereof, for the manufacture of a composition forntransdermal administration by iontophoresis. |