| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c22c6d06e5563aee18cc3c610cfa6180 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-08 |
| filingDate |
2004-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9870957131dc1ab8ba2e61046f0e9708
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76443f9dda85c9177125c8c795281dbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c7ffe64b4e4aa864b2f50f631c56aac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3c0bda870aed12fcc400d5ad10e28b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dec48c99bac05b454c8e8f6c9a76b888
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c35fdf5bd8135bd195d4ab33c4614ac2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f6bb6d95ff1b11fae0c6f771d6f3188
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3486655c0b9ee181e84eac0fddbfe217 |
| publicationDate |
2006-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1589341-A3 |
| titleOfInvention |
Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures |
| abstract |
The present invention describes a method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixture. The method comprises the selective isolation from every protein of those peptides that neither contain arginine nor histidine (NHNR peptides), and the determination of the relative concentrations of one or several proteins in different samples from the ratio between the areas of the estimated theoretical spectra for the NHNR peptides labeled with different isotopes in each sample. The determination of the relative concentration of proteins is valid for any type of isotopic label of the NHNR peptides. The method avoids the separation and purification of the proteins present in a complex mixture, and the analysis of all peptides generated from the enzymatic digest of the samples. The method is applicable to the identification of proteins with vacunal, therapeutic and diagnostic aims. |
| priorityDate |
2003-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |