http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1586662-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41686a979f961bce6a9855b4b409a5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2005-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_630465f9e4989bd0ca857e52027ab388 |
| publicationDate | 2005-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1586662-A1 |
| titleOfInvention | Nucleic acid detection method using multiple pairs of donor flurophores and quencher molecules in the same probe |
| abstract | A detector oligonucleotide comprises multiple pairs of a donor fluorophore and a quencher molecule, which donor fluorophores and quencher molecules are separated by a site that is capable of being cleaved when in double-stranded form. The detector oligonucleotide may be made double-stranded in a manner that depends on the presence of a target nucleic acid, allowing the cleavage sites to be cleaved. Separation of the donor fluorophores and the quencher molecules decreases fluorescence quenching and generates a detectable change in a fluorescence parameter of the fluorophores of the detector oligonucleotide. By using multiple donor/quencher pairs, the present detector oligonucleotide advantageously generates a high signal to noise ratio and high efficiency in detection of a target nucleic acid. <IMAGE> |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1911852-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008044129-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008044129-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11674178-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8586718-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020123961-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9194007-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006031851-A1 |
| priorityDate | 2004-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.