abstract |
In one aspect of the invention a multi-balloon catheter (10), such as a double-balloon catheter, with coating comprising a hydrogel polymer on the exterior surface of the occlusion balloons (40) is provided. The balloons (40) may be inflated inside the lumen to occlude a plaque-affected segment of the lumen thereby forming a lumen space between the balloons (40), wherein this plaque-affected lumen segment may be treated with a biologically active agent. The presence of the coating can reduce de-nuding of healthy endothelial lumen tissue after contact with the inflated balloons (40) during the occlusion. |