| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3632a9cdbb326003fb5ca03af8d14560
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b18d1db59461d7a871ab12f72a4fd5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b0d32771d9c94f87613707e3fd7a6d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2d76dac286bc6fb50f130f90520d06a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-57 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2003-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_916b767939bd541cc01c3373c9057c4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7240ce43704c558bc2975d87abd54f24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_685c22a4d9fa326a456d664fe6fa1400
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b5f4d2286f9ce3975b3e72e0f60854b |
| publicationDate |
2012-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1575526-B1 |
| titleOfInvention |
Dna vaccines encoding heat shock proteins |
| abstract |
The present invention is related to recombinant constructs encoding heat shock proteins or active fragments thereof, effective in treating T cell mediated inflammatory autoimmune diseases by DNA vaccines. The treatment with the recombinant constructs of the present invention provides long-term expression of specific heat shock proteins for fragments thereof. In one embodiment, the present invention is related to a recombinant construct comprising a nucleic acid sequence encoding HSP60, HSP70 or HSP90. In various preferred embodiments, the present invention is related to a recombinant construct comprising a nucleic acid sequence selected from amino acids 1-140 of HSP60, amino acids 130-260 of HSP60 and amino acids 31-50 of HSP60. Another aspect of the present invention is related to an active fragment of HSP60 corresponding to amino acids 31-50 of HSP60 effective in treating arthritis. |
| priorityDate |
2002-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |