| abstract |
The present invention is concerned with proteins selected from thenmembers of the TGF-β superfamily, which are monomeric due tonsubstitution or deletion of a cysteine which is responsible for dimernformation. n The invention is also concerned with nucleic acids, encoding suchnmonomeric proteins, vectors or host cells containing the nucleic acids asnwell as with pharmaceutical compositions comprising the proteins or nucleicnacids encoding the proteins. The pharmaceutical compositions can benapplied advantageously for all indications for which the respective dimericnproteins are useful. |