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filingDate 2003-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2006-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1572989-B1
titleOfInvention Gen 2.2 dendritic cell line
abstract Isolated cell line (A) comprises human plasmacytoid dendritic cells (hPDC) of phenotyype CD4+, HLA DR+, CD123+, CD45RA-, CD11c- and CD13-. Independent claims are also included for: (1) in vitro culture and multiplication of a line of hPDC by culturing them on adherent stromal cells (ASC) in medium; (2) in vitro isolation of a line of hPDC; (3) cell lines isolated by method (2); (4) in vitro preparation of activated hPDC; (5) in vitro activation of T cells, using (A); and (6) identifying compounds (X) that activate hPDC.
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