| abstract |
The present invention provides novel a-glucosidase inhibitory compound (-)-mesquitol and its analogs isolated in significant yield from traditional medicinal plant Dichrostachys cinerea and further modification of (-)-mesquitol to enhance the a-glucosidase inhibitory potential; the invention also identifies the usage of (-)-mesquitol and its analogues, based on their a-glucosidase inhibitory activity, as broad based potential therapeutics as antihyperglycemic, antidiabatic, antiobesity, antiviral, anticancer, immunestimulants and the like. |