Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ce08fe8a4ef978a21143f754fd70f1d |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-108 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-10 |
filingDate |
2003-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae989a126cd5b2e8cc5e7ea21531c609 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ff20120f0aa5d86b8f7abd3b7ed0307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0e800ee6ad6ec0879029c14c9a8f983 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9954b388961be83f3a7e4afb702f933 |
publicationDate |
2006-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1567510-B1 |
titleOfInvention |
Method for producing salts of tolperisone |
abstract |
The invention relates to a method for producing an acid addition salt of 2,4'-dimethyl-3-piperidino-propiophenone (tolperisone) with a pharmaceutically acceptable acid, of the formula (I). According to the invention, 4-methylpropiophenone is reacted with piperidine hydrochloride and 1,2-dioxolane in the presence of an acid serving as a catalyst, and the tolperisone obtained in the form of an acid addition salt is separated by filtering after the reaction mixture has cooled down. |
priorityDate |
2002-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |