| abstract |
The invention relates to therapeutic compositionsnin the field of angiogenesis, including sequencesnnucleotides of genes that have been shown to beninvolvement in the mechanism of angiogenesis includingntheir complementary sequences, the antisense sequences,npolypeptide sequences encoded by the partiesncoding of said genes as well as directed antibodiesnagainst said polypeptide sequences.n n n The invention also relates to geneticallynunder-expressing or overexpressing said genes,ntherapeutic compositions the containers, useful for thentreatment of angiogenic disorders.n n n The invention also relates to diagnostic methodsnand / or prognosis of angiogenic disorders as well asnnew methods of screening active compounds in thentreatment of said disorders. |