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filingDate 2003-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95aa2924518c7cd0d718c512187638c2
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publicationDate 2005-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1565479-A2
titleOfInvention 2'-o-trisubstituted silyloxymethyl-ribonucleoside-derivative and method for preparing the same
abstract The invention provides ribonucleoside derivatives with novel protecting groups and methods for the preparation of such ribonucleoside derivatives. The general formula (I) of the ribonucleoside derivatives is: wherein R<SUB>1 </SUB>is a base of the purine- or pyrimidine-family or a derivative of such a base or any other residue with serves as a nucleobase surrogate, R<SUB>2 </SUB>is a proton or a substituted derivative of phosphonic acid, R<SUB>3 </SUB>is a proton or a protection-group for the oxygen atom in 5'-position, R<SUB>4</SUB>, R<SUB>5 </SUB>and R<SUB>6 </SUB>are independently alkyl or aryl or a combination of alkyl and aryl or heteroatom, R<SUB>4</SUB>, R<SUB>5 </SUB>or R<SUB>6 </SUB>may also be cyclically connected to each other; and wherein at least one of the R<SUB>4</SUB>, R<SUB>5 </SUB>or R<SUB>6 </SUB>substituents comprises a tertiary C-atom or a heteroatom vicinal to the Si-atom.
priorityDate 2002-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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