| abstract |
Polyacrylamide hydrogels comprising less than 3.5% polyacrylamide, cross-linked with methylene-bis-acrylamide, and at least 95% water or saline solution were found to be stable. These hydrogels are useful as injectable or implantable endoprosthetic devices for use in mammoplasty, soft tissue filling, penile augmentation, facial correction, lip augmentation, body contouring, arthritis, incontinence, reflux oesophagitis, and vesicouretal reflux. Hydrogels comprising from 0.5 to 25 % polyacrylamide hydrogel are described as well as for use as prosthetic devices. The hydrogels are tailored to their intended use as prosthetic devices, in terms of their physical and rheological properties, such as their polyacrylamide content, viscosity and elasticity. |