| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ae609b1f14b3fb56a927f7b5c15b67 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-285
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-1807
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J41-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3285
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3293
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J39-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-286 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-286
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-285
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-281
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-30 |
| filingDate |
2003-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a0c70862dfe82c419db9df64dab8051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c1ac3ff86faca13c18ac91818c48857
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b8f297a4bbc18a79096b75559612d2e |
| publicationDate |
2005-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1558927-A1 |
| titleOfInvention |
Chromatographic two-layer particles |
| abstract |
The present invention is a method of producing a chromatographic separation matrix, wherein porous polymeric particles comprised of two layers with different properties are prepared in a two-phase system by (a) providing porous polymeric particles with reactive groups on their surfaces; (b) washing said particles with a first solvent and draining the particles to enclose a first phase; (c) wetting the outer layer of the particles by adding a second solvent, which is essentially insoluble in the first solvent; (d) reacting the reactive groups in the outer layer by adding a reagent, which is essentially non-reactive in the first solvent; and (e) coupling of chromatographic binding groups to the reactive groups in the inner layer. The invention also encompasses a porous polymer particle suitable for use as a chromatographic separation matrix and a process of separation, wherein a matrix according to the invention is used. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2821321-A3 |
| priorityDate |
2002-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |