abstract |
A process for preparing a paroxetine hydrochloride hydrate, comprisingnreacting (3S, 4R)-1-tert-butoxycarbonyl-4-(4-fluorophenyl)-3-[(3,4-methylenedioxy)phenoxymethyl]piperidinenwith hydrogen chloride in the presence of water,nand allowing crystals to separate out from the resulting reaction mixture in thenpresence of water. |