http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1552887-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c16d2144a81bfa32a665dca1e93c3d37 |
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| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-0262 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-0268 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B60-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N35-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-02 |
| filingDate | 2004-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3fb9260b7a44149f3e61c7e5cd54d55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c10e81fdd9caa477dede83e8cef8c5b5 |
| publicationDate | 2005-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1552887-A2 |
| titleOfInvention | Device and method for printing biomolecules onto substrate using electrohydrodynamic effect |
| abstract | A device and a method for printing biomolecules onto a substrate using annelectrohydrodynamic (EHD) effect are provided. The device for printingnbiomolecules onto a substrate using an electrohydrodynamic (EHD) effect includesnat least one capillary having an outlet through which a feeding solution ofnbiomolecules selected from the group consisting of nucleic acids, proteins, andnoligopeptides is discharged, the nucleic acids being selected from the groupnconsisting of probe DNA, RNA, peptide nucleic acid (PNA), and LNA and thenproteins being selected from the group consisting of antigen and antibody; a printernbody supporting the at least one capillary; a substrate below the outlet having antarget surface onto which the biomolecules are deposited; a first electric field formingnelectrode located on the printer body around the circumference of the outlet; ansecond electric field forming electrode spaced apart from the first electrode by anpredetermined distance; and a voltage applying unit which is electrically connectednto the first electrode and the second electrode to apply an alternating current (AC)nvoltage between the first electrode and the second electrode so that an electric fieldnmay be formed around the biomolecule solution suspended in the outlet, and due tonthe interaction of the electric field and a difference in dielectric constant between thenbiomolecule solution having a free surface and the surrounding atmosphere, thenelectric force acts inward on the biomolecule solution from the surroundings, therebyndropping a predetermined amount of the biomolecule solution onto the target surfacenof the substrate. By using an EHD effect, the advantages of the device and methodnare that the process is quick, the biomolecule spots are uniform and easily aligned,nand especially it is possible to spot the biomolecules correctly and reproducibly evennwhen the printer body is not fully aligned with the substrate. In addition, the devicenand method are applicable to proteins which are sensitive to heat and biomoleculesnwhich have neutral charges. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1759759-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102529366-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017081457-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102529366-B |
| priorityDate | 2004-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.