http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1552008-A4
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00affd34ba73b901cd18730ddb677244 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-682 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-547 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
| filingDate | 2003-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_193a9c2957503914949480985bf99ed5 |
| publicationDate | 2007-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1552008-A4 |
| titleOfInvention | MICROPARTICLE-BASED SIGNAL AMPLIFICATION FOR ANALYTE DETECTION |
| abstract | Microparticle based amplification (MBA) for high sensitivity and high speed analyte detection is described. MBA is based on signal amplification achieved by use of a signal amplification microparticle (10) that contains a plurality of signaling molecules (20) attached to a plurality of positions on the surface (15) of the microparticle (10), in combination with a plurality of analyte binding molecules attached to a plurality of positions on the surface. Each signaling molecule in turn has a plurality of signal emitting moieties (25 & 28), such as acridinium, attached thereto. This is combined with a separating microparticle such as a ferromagnetic particle, also having an analyte binding molecule attached to the surface so that a complex comprising the analyte, the signal amplification microparticle and the separating microparticle is formed. The complex emits a signal that is amplified many fold relative to the stoichemetric amount of analyte molecules in the sample. Particular embodiments include methods for detecting bacteria, antigens, antibodies and nucleic acids. |
| priorityDate | 2002-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.