| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e13e2baa17ad864a5ae6fde5b17e5eb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-307 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C243-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-307
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-16 |
| filingDate |
2003-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a72678707ab869e13e6a0e726eed5441
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90518736ab756044a189078ef29d02d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ced733775f50ade26cdf10e7cb21bb94 |
| publicationDate |
2007-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1551796-A4 |
| titleOfInvention |
IMPROVED SYNTHETONE SYNTHESIS |
| abstract |
The present disclosure relates to an improved synthesis of the commercially important syntheton ECHB starting from the readily available 3-hydroxy-Ϝ-butyrolactone. The reaction employs a single pot procedure without isolation or purification of the intermediates. It has the advantage over procedures previously employed in the art of using reagents and conditions which minimize undesired side reactions and which can be readily employed at commercial scale. The product is produced in high yield and is readily purified to provide an excellent intermediate for further synthesis of commercially important products such as L-carnitine and the pharmaceutically important active substances used in HMG-coA reductase inhibitor products such as Lipitorè. |
| priorityDate |
2002-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |