http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1549650-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44e0905262f429c7590b40df8448c0c5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2003-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_966e1a97b7e23213202343d0fd3ece3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa1c60d47aa6194281b9ba9762eead7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d3dc8e806265fc04d0fb5af39993197 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b89bff769e18fe3a6e971fc6bfc62826 |
| publicationDate | 2005-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1549650-A1 |
| titleOfInvention | Substituted c-imidazo[1,2-a]pyridin-3-yl-methylamines |
| abstract | Substituted C-(imidazo-(1,2-a)-pyridin-3-yl)-methylamines (I) are new. Imidazo-pyridine derivatives of formula (I), optionally in the form of racemates, pure stereoisomers (especially enantiomers or diastereomers) or their mixtures in all proportions and in acid, base, salt or solvate (specifically hydrate) form, are new. R1 = OH, SH, NH2, NHMe, NMe2, Me, CH2Cl, CH2F, CHF2, CF3, OMe, OCH2Cl, OCH2F, OCHF2, OCF3, Et, CHClMe, CH2CH2Cl, CHFMe, CH2CH2F, CH2CHF2, CH2CF3, OEt, COOH, CH2OH, CH(OH)Me, CH2CH2OH, CN or halo; R2 = H or Me; R3 = H or COOR10; or (all optionally substituted) optionally unsaturated 1-6C alkyl, optionally unsaturated 3-8C cycloalkyl, 2-methylcyclopropyl, cyclopropylmethyl, 2- or 3-methylcyclobutyl, cyclobutylmethyl, aryl or heteroaryl; R4 = H or heterocyclic group of formula (a); or (all optionally substituted) optionally unsaturated 1-12C alkyl, optionally unsaturated 3-8C cycloalkyl, 2-methylcyclopropyl, cyclopropylmethyl, 2- or 3-methylcyclobutyl or cyclobutylmethyl; n, m = 0-6, provided that n + m = 1-6; X = O, S, SO, SO2 or NR7; R = H, halo, OH, SH, NH2, NO2, Me, Et, OMe, OEt or OCF3; R5 = H; or (all optionally substituted) optionally unsaturated 1-6C alkyl, optionally unsaturated 3-8C cycloalkyl, 2-methylcyclopropyl, cyclopropylmethyl, 2- or 3-methylcyclobutyl or cyclobutylmethyl; R6 = H or R14-unsubstituted 2-pyridinyl; or (all optionally substituted) optionally unsaturated 1-6C alkyl, optionally unsaturated 3-8C cycloalkyl, 2-methylcyclopropyl, cyclopropylmethyl, 2- or 3-methylcyclobutyl or cyclobutylmethyl; or NR5R6 = morpholino, 4-(R11)-piperazino, azetidino, pyrrolidino, piperidino or homopiperidino; R7 = H, 1-6C alkyl, 3-8C cycloalkyl, 2-methylcyclopropyl, cyclopropylmethyl, 2- or 3-methylcyclobutyl, cyclobutylmethyl, COR8 or SO2R9; R8 - R10 = H, 1-6C alkyl or aryl; R11 = H, 1-6C alkyl, 3-8C cycloalkyl, aryl, heteroaryl, aryl-(1-3C) alkyl, heteroaryl-(1-3C) alkyl, COR12 or SO2R13; R12, R13 = H, 1-6C alkyl or aryl; and R14 = H, halo, OH, SH, NH2, NO2, Me, Et, OMe, OEt or OCF3. Provided that the compounds (7-methyl-imidazo-(1,2-a)-pyridin-3-ylmethyl)-dimethylamine and C-(7-methyl-imidazo-(1,2-a)-pyridin-3-yl)-methylamine are excluded. |
| priorityDate | 2002-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 172.