| abstract |
The present invention concerns a method for coatingngranules comprising mesalazine, with a coating mixturencomprising two polymers, polymer I and polymer II; saidnpolymer I being selected to allow formation of a closingnmembrane around said granules in the absence of saidnpolymer II, and said polymer II being selected to act asna water-soluble pore former in said coating mixture;nwherein a) the amount of polymer I is adjusted to providena closing membrane in the absence of polymer II, and b)nthe amount of polymer II in said coating mixture is adjustednto obtain coated granules which exhibit controllednrelease of mesalazine. The invention further concerns anproduct obtainable by the coating method. |