http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1544210-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b65daff6c2ca212ed1cecda3a870a70 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate | 2003-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb15a9d8cb12dd8ed111130a9530e02b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebc2b163f27015505a3dcfae8f1ef8ea |
| publicationDate | 2005-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1544210-A1 |
| titleOfInvention | Novel notch-origin polypeptides and biomarkers and reagents using the same |
| abstract | It is intended to provide extracellular markers whereby Notch signal transduction cannbe detected. Polypeptides (Nβ), which are novel peptides originating in Notch proteinnand released form cells in the step of the nuclear migration of NICH (Notchnintracellular cytoplasmic domain) due to the extracellular digestion and thensubsequent protein digestion in the membrane during a series of the Notch proteinndigestion, are referred to as markers. These peptides (Nβ) are released from the cellsnin proportion to the Notch signal depending on presenilin. By detecting thesenpeptides, the Notch signal transduction, cell differentiation, cell tumorigenesis,napoptosis, Alzheimer's disease, etc. can be monitored. |
| priorityDate | 2002-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 166.