abstract |
Provided is an external preparation compositionnused for preventing or treating symptoms or diseasesnrelated to dermatopathy caused by dryness, UV rays andnaging such as wrinkles and sags of the skin, pigmentationnof the skin, skin roughness and coarse texture and skinndiseases such as psoriasis, lichen, ichthyosis, keratosis,nDarier's disease, pustulosis, acne, eczema and atopicndermatitis. n The above external preparation composition isn characterized by comprising at least one of acylnglucosamine derivatives represented by the followingnFormula (I):n nwherein R 1 , R 2 , R 3 and R 4 represent a hydrogen atom, ansaturated or unsaturated, linear or branched fatty acidnresidue having 2 to 36 carbon atoms or a linear ornbranched alkyl group having 1 to 4 carbon atoms which maynhave a hydroxyl group, and they may be the same orndifferent each other; R 5 represents a hydrogen atom or anlinear or branched alkyl group having 1 to 4 carbon atomsnwhich may have a hydroxyl group; X is any one of groupsnrepresented by the following Formulas (A) to (C): n nwherein Y in the formulas (A) and (B) described abovenrepresents a hydrogen atom or an alkyl group having 1 ton5 carbon atoms in which an ether group may be interposednbetween a bond; and n represents an integer of 0 to 10;nand R 6 represents a linear or branched alkyl group ornalkenyl group having 11 to 36 carbon atoms which may havena substituent. |