| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a60649a09a47690f2c5082c03fbc2212
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df874e3cf88adba3792dc9d5b5776180
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2510-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56988 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| filingDate |
2003-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96189f268cb8c591cb7c455df5b8881d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f22afc2f4d77be289079f040adb86cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a33e6493ee31d5242d747146e36bd3a |
| publicationDate |
2005-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1542016-A1 |
| titleOfInvention |
PUMA, phosphorylated p53 and p38 map kinase as markers for HIV-1-induced apoptosis in circulating T cells of infected patient |
| abstract |
The subject matter of the present invention relates to an in vitro method for thenscreening of anti-HIV compounds, or for predicting the progression of HIV related diseases, ornfor determining the efficiency of an anti-HIV-1 treatment based on the measuring of thenexpression level of Puma and, optionally, on the measuring of the phosphorylated p53 and/ornthe p38 MAP kinase protein level in circulating white blood cells of a sample from a HIVninfected patient, particularly HIV-1. The invention further comprises a method for thendiagnostic of HIV infection in a patient and kits for performing these methods. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007130523-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012009347-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7662547-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012009347-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2861788-A4 |
| priorityDate |
2003-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |