http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1539939-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_313c2ac1c6159e38a96bd17d83b17a2b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-22022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-22023 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0041 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 |
| filingDate | 2003-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d45173b6f2d3b370b136efdba952c20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5ebaeb4d512859b95cea28172c7a409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3a441cb0912ff09c7159f7bc25d2e4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_451f94aff8e28a235a481e22ffadea1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5130a48bb824e6592265abfb4beff749 |
| publicationDate | 2005-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1539939-A1 |
| titleOfInvention | Method for the production of virus-analog particles for packing biologically active macromolecule by in vitro assembly of capsomers to which the macromolecules are bound |
| abstract | Virus-analog particles are predominantly produced recombinantly. Recombinant expression of capsomers in Escherichia coli makes it possible to obtain non-assembled capsomers which can be assembled in vitro. However, the degree of assembly is low. In fact, in vitro assembly into virus-analog particles is prevented if the macromolecules are bound to the capsomers. Complexes with macromolecules can only be obtained by interaction of the macromolecules with the already assembled virus-analog capsomers. The degree of packing of the macromolecules is nevertheless low. Virus-analog particles are produced by means of a method for the production of virus-analog particles by in vitro assembly of capsomers or capsomers, biologically active macromolecules being bound to the charged amino acids of said capsomers with simultaneous packing to macromolecules in the presence of non-ionic stabilizers. Said complexes are suitable vectors for gene therapy. |
| priorityDate | 2002-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.